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Table 3 Risk of Recurrence of Biliary Obstruction in Patients with Unresectable Malignant Biliary Obstruction after Therapy

From: The safety and efficacy of percutaneous intraductal radiofrequency ablation in unresectable malignant biliary obstruction: A single-institution experience

  

Univariate Analysis

Multivariate Analysis

Variable*

No. of cases

HR(95%CI)

P†

HR(95%CI)

P

Age(≥62 y vs < 62 y)

25/25

2.348(0.840,6.566)

0.104

  

Sex(male vs female)

36/14

1.243(0.404,3.827)

0.705

  

Tumor diagnosis (Cholangiocarcinoma vs other neoplasms)

25/25

1.770(0.679,4.612)

0.243

  

Type of obstruction(proximal vs distal)

19/31

0.899(0.324,2.494)

0.838

  

Performance status score (2 vs ≤1)

32/18

1.706(0.890,3.270)

0.108

  

Previously cholangeitis (no vs yes)

28/22

3.347(1.176,9.525)

0.024

3.347(1.176,9.525)

0.024

Distant Metastasis(yes vs no)

29/21

1.292(0.490,3.403)

0.605

  

Chemotherapy (no vs yes)

43/7

0.840(0.277,2.547)

0.759

  

TB(≥168.0 μmol/L vs <168.0 μmol/L)

25/25

0.488(0.184,1.294)

0.149

  

DB(≥95.1 μmol/L vs < 95.1 μmol/L)

25/25

0.485(0.183,1.287)

0.146

  

ALT (≥71 U/L vs <71 U/L)

25/25

1.352(0.491,3.728)

0.560

  

AST (≥72.5 U/L vs < 72.5 U/L)

25/25

0.887(0.348,2.261)

0.801

  

GGT(≥311 U/L vs < 311 U/L)

25/25

0.613(0.228,1.652)

0.334

  
  1. Note—TB = total bilirubin, DB = direct bilirubin, ALT = alanine aminotransferase, AST = aspartate aminotransferase, G-GT = gamma-glutamyl transpeptidase
  2. *For continuous variables, cutoff level chosen for continuous variables was their median value
  3. P values were determined with Cox proportional hazards regression models. P < 0 .05 indicated a significant difference