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Table 1 The immunophenotypes of 42 cases of RCCs with sarcomatoid differentiation and the expression differences between carcinoma and sarcomatoid differentiation

From: Distinct immunophenotypes and prognostic factors in renal cell carcinoma with sarcomatoid differentiation: a systematic study of 19 immunohistochemical markers in 42 cases

Markers C+/S+ C+/S- C−/S+ C−/S- Total C+ Total S+ P value
Vimentin 22 0 20 0 22 (52%) 42 (100%) 0.000*
CK 18 16 3 5 34 (81%) 21 (50%) 0.005*
EMA 21 16 0 5 37 (88%) 21 (50%) 0.000*
CK7 0 11 5 26 11 (26%) 5 (12%) 0.164
CK18 12 13 7 10 25 (60%) 19 (45%) 0.275
HMW-CK 0 0 3 39 0 (0%) 3 (7%) 0.241
CAIX 20 1 12 9 21 (50%) 32 (76%) 0.023*
CD10 20 3 12 7 23 (55%) 32 (76%) 0.065
PAX8 24 10 3 4 34 (81%) 27 (64%) 0.141
AMACR 3 8 3 28 11 (26%) 6 (14%) 0.277
CD117 0 7 3 32 7 (17%) 3 (7%) 0.313
CD99 0 3 9 30 3 (7%) 9 (21%) 0.116
SMA 0 0 8 34 0 (0%) 8 (19%) 0.005*
CD34 0 0 0 42 0 (0%) 0 (0%)
S100 0 0 0 42 0 (0%) 0 (0%)
HMB45 0 0 0 42 0 (0%) 0 (0%)
MelanA 0 0 0 42 0 (0%) 0 (0%)
P53 8 2 12 20 10 (24%) 20 (48%) 0.040*
Bcl-2 9 16 0 17 25 (60%) 9 (21%) 0.001*
  1. C carcinoma cell, S sarcomatoid cell
  2. *The difference is statistically significant