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Table 4 Impact of serum KL-6 on the prognosis of lung adenocarcinoma

From: MUC1 in lung adenocarcinoma: cross-sectional genetic and serological study

Variable HR 95% CI. P value
A. Multivariate Cox proportional hazards regression model
PS, ordinal 1.72 1.35–2.20 <0.001
EGFR, wild type / mutant 2.43 1.62–3.64 <0.001
N factor, ordinal 1.23 1.04–1.45 0.018
M factor, yes / no 3.33 2.02–5.48 <0.001
Serum KL-6, ≥600 / <600 U/mL 2.19 1.43–3.37 <0.001
B. Comparison of C statistics for each prediction model
Prediction model C index 95% CI. P value
Covariates only 0.776 0.722–0.830 Ref.
Covariates + serum KL-6 0.790 0.736–0.843 0.036
  1. “Covariates” in C statistics included PS, EGFR mutation status, and N and M factors. PS performance status