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Table 4 Impact of serum KL-6 on the prognosis of lung adenocarcinoma

From: MUC1 in lung adenocarcinoma: cross-sectional genetic and serological study

Variable

HR

95% CI.

P value

A. Multivariate Cox proportional hazards regression model

PS, ordinal

1.72

1.35–2.20

<0.001

EGFR, wild type / mutant

2.43

1.62–3.64

<0.001

N factor, ordinal

1.23

1.04–1.45

0.018

M factor, yes / no

3.33

2.02–5.48

<0.001

Serum KL-6, ≥600 / <600 U/mL

2.19

1.43–3.37

<0.001

B. Comparison of C statistics for each prediction model

Prediction model

C index

95% CI.

P value

Covariates only

0.776

0.722–0.830

Ref.

Covariates + serum KL-6

0.790

0.736–0.843

0.036

  1. “Covariates” in C statistics included PS, EGFR mutation status, and N and M factors. PS performance status