Table 2 Univariate and multivariate analysis for the identification of predictive factors of recurrence
From: Is adjuvant chemotherapy necessary in pT1N1 gastric cancer?
Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Age | ||||||
≤ 65 | ||||||
> 65 | 2.625 | 1.384–4.981 | 0.003 | 2.541 | 1.336–4.831 | 0.004 |
Gender | ||||||
Female | ||||||
Male | 2.401 | 1.101–5.240 | 0.028 | 2.217 | 1.013–4.854 | 0.046 |
BMI (kg/m2) | ||||||
≥ 25 | ||||||
< 25 | 2.599 | 1.086–6.216 | 0.032 | 2.400 | 1.001–5.759 | 0.050 |
Type of resection | ||||||
Subtotal | ||||||
Total | 0.718 | 0.221–2.334 | 0.581 | |||
Tumor location | ||||||
Upper | ||||||
Middle | 0.871 | 0.193–3.932 | 0.857 | |||
Lower | 1.167 | 0.276–4.928 | 0.834 | |||
Gross type | ||||||
Non-elevated | ||||||
Elevated | 2.063 | 1.054–4.037 | 0.035 | 1.821 | 0.929–3.570 | 0.081 |
Depth of invasion | ||||||
Mucosa | ||||||
Submucosa | 3.464 | 0.834–14.394 | 0.087 | |||
No. of metastatic LN | ||||||
One | ||||||
Two | 1.194 | 0.623–2.288 | 0.594 | |||
No. of negative LN | 0.996 | 0.975–1.017 | 0.697 | |||
Lymphatic invasion | ||||||
Negative | ||||||
Positive | 1.800 | 0.939–3.454 | 0.077 | |||
Histologic type | ||||||
Undifferentiated | ||||||
Differentiated | 2.251 | 1.163–4.356 | 0.016 | 1.548 | 0.776–3.087 | 0.215 |
Adjuvant CTx | ||||||
No | ||||||
Yes | 0.919 | 0.455–1.859 | 0.815 | 0.952 | 0.467–1.937 | 0.891 |