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Fig. 1 | BMC Cancer

Fig. 1

From: Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns

Fig. 1

a Histogram of differentially methylated CpGs (LME, FDR < 0.05). Blue represents CpGs that have significantly higher methylation in benign-adjacent prostate tissue when compared to prostate cancer tissues (73,912 CpGs), and red represents CpGs that have significantly higher methylation in prostate cancer tissues (152,324 CpGs). b Heatmap of the top 10,000 CpGs with the most statistically significant DNA methylation differences between unaffected prostate tissue and prostate cancer tissue based on LME p-value. Color bar represents beta score with 0.5 subtracted

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