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Fig. 3 | BMC Cancer

Fig. 3

From: Tiamulin inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of CD73

Fig. 3

THF inhibited CD73 by down-regulating the activity instead of the expression of CD73. a and b Effect of THF on CD73 activity in breast cancer cells. After treatment with THF (12.5 or 25 μg/mL), CD73 activity significantly decreased in (a) MDA-MB-231 and (b) 4 T1 cells. c and d Western Blotting showing the expression of CD73 after 36 h treatment with solvent or 12.5, 25 μg/mL THF. Similar results were obtained from independent experiments in (c) MDA-MB-231 and (d) 4 T1 cells. Data represent the mean ± S.D. of three independent experiments. (*P < 0.05, **P < 0.01 vs control)

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