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Table 1 Characteristics of included randomized trials

From: Effects of omega-3 fatty acids on patients undergoing surgery for gastrointestinal malignancy: a systematic review and meta-analysis

Trial(year) Time Country Intervention n-3 PUFA,n Contro l, n Age BMI Cancer Studu design Parameters
Ma et al. [12] 2015 China 0.8–1.5 g/kg/d LCT,MCT, n-3PUFA 44 41 61.55 ± 9.78 23.45 ± 3.44 44 stomach, colon Randomized IL-6, CRP, TNF-α
Ziran et al. [13] 2014 Brazil 104–125 kJ/kg/d EPA + DHA 26 20 36–74 17.8–29.7 stomach Randomized CD3, CD4, CD8, CD4/CD8, albumin, L-6, CRP, TNF-α
Liu et al. [14] 2009 China 83.68 kJ/kg/d n-3PUFA 22 20 64.02 Not Given stomach, colon Randomized CD3, CD4, CD8, CD4/CD8, albumin, CRP
Hu et al. [15] 2015 China 104–125 kJ/kg/d n-3PUFA 44 44 23–78 Not Given stomach, colon Randomized CD3, CD4, CD8, CD4/CD8, IL-6, CRP, TNF-α
Zheng et al. [16] 2011 China 25 kcal//kg/d n-3PUFA 20 20 56.19 ± 11.80 Not Given colon, rectum Randomized CD3, CD4, CD4/CD8, albumin, CRP
ZHU et al. [17] 2012 China 1.2 g/kg/d n-3PUFA 29 28 70.8 ± 6.4 18.5–25.0 colon Randomized CD4, CD8, CD4/CD8, IL-6, TNF-α
Aoife et al. [18] 2009 Ireland 2.2 g/d EPA 28 25 62 24.6 esophagus Randomized albumin, IL-6
Huang et al. [19] 2014 China 25 kcal//kg/d n-3PUFA 40 40 60.88 ± 7.54 Not Given esophagus Randomized CD3, CD4, CD8, CD4/CD8
Sultan et al. [20] 2012 UK EPA 0·51 g/100 ml + DHA 0·22 g /100 ml 66 66 67 (42–79) Not Given esophagus, stomach Randomized CD3, CD4, CD8, CD4/CD8
  1. LCT long-chain triglyceride, MCT medium-chain triglyceride