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Table 1 Genes regulated after treatment of the indicated ovarian cancer cell lines with the specific ERβ agonists ERB-041, Liquiritigenin (LIQ.) and WAY − 2,000,070 for 48 h. Shown are genes with at least 2-fold regulation in one experimental setting (values in italics). Data were assessed by means of Affymetrix GeneChip 1.0 microarray analyses and are expressed in -fold change compared to the vehicle control

From: Effect of estrogen receptor β agonists on proliferation and gene expression of ovarian cancer cells

  OAW-42 OVCAR-3
ERB-041 LIQ. WAY200070 ERB-041 LIQ. WAY200070
Up-regulated genes
 C6ORF99 2,52 3,81 1,91 1,35 1,01 -1,17
 TPTE2 1,67 2,05 2,26 1,05 1,22 1,08
 CD177 1,55 −1,08 2,14 1,53 1,62 1,79
Down-regulated genes
 LINC00314 1,24 -1,26 -1,44 -1,86 −2,09 -2,71
 EPCAM -1,35 −1,41 -2,20 −1,21 -1,02 -1,05
 SNORD25 -2,07 −1,07 −2,00 −1,03 −1,11 -1,07
 RNU4-2 -1,46 −2,09 −1,49 −1,16 −1,21 -1,03
 RNU2-1 -1,62 -1,57 −2,05 −1,29 −1,03 -1,30
 PTCH2 -1,67 −1,76 −2,08 −1,37 −1,10 -1,33
 RNU5B-1 -1,51 -1,79 −2,54 −1,11 −1,23 -1,09
 ND6 -2,11 −2,12 −4,01 −1,38 −1,11 1,42
 FAM48B2 -1,29 −1,30 −1,73 −2,11 −1,72 -1,76
 LCN1 -2,28 −1,12 −1,11 −2.14 −2,38 -1,61
 SNORA1 -1,82 −2,07 −2,09 −1,39 −1,41 −1,71