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Fig. 5 | BMC Cancer

Fig. 5

From: Effect of estrogen receptor β agonists on proliferation and gene expression of ovarian cancer cells

Fig. 5

Effect of ERβ agonists on gene expression (Affymetrix GeneChip analysis). a Regulation of growth-associated genes cyclin E2 and growth arrest specific 2 (GAS2) after treatment with the agonists ERB-041 (β41), Liquiritigenin (LIQ), WAY200070 (WAY) or the vehicle control (con) for 48 h (10 nM) *p < 0.05 bs. Vehicle. b Network connecting ESR2 with the genes LCN1, EPCAM, PTCH2 and ND6 being downregulated by ERβ agonists in this study. Broken lines: direct binding. Solid lines: affecting expression. Prediction by IPA Software (Ingenuity Pathway Analysis, Ingenuity Systems, Stanford, USA) [54,55,56,57,58,59,60,61]

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