Weight change during chemotherapy in breast cancer patients: a meta-analysis

BMC Cancer

Table 4 Results from multivariate meta-regression analysis on weight change in subgroups of early stage breast cancer patients during chemotherapy

	Unadjusted				Adjusted^d
	RC^a	SE^b	95% CI^c	P-value	RC	SE	95% CI	P-value
Type chemotherapy
No CMF	ref				ref
CMF included	2.2	0.6	1.1, 3.3	<0.01	1.4	0.6	0.3, 2.6	0.02
Menopausal status
Premenopausal	ref
Postmenopausal	−1.3	1.4	−4.1, 1.5	0.36
Perimenopausal	2.2	1.8	−1.5, 5.8	0.23
Combination	0.1	0.8	−1.5, 1.6	0.91
Follow-up
end of chemotherapy / 6 months after baseline	ref
6 months after chemotherapy / 12 months after baseline	−0.1	0.1	−0.3; 0.2	0.64
Type of studie
Chart review	ref				ref
Prospective	−2.0	0.6	−3.1, −0.8	<0.01	−0.7	0.6	−1.9, 0.5	0.24
Publication year
After 2000	ref				ref
Before and including 2000	1.9	0.6	0.8, 3.1	<0.01	1.3	0.5	0.2, 2.3	0.02
Sample Size
≤ 100	ref
> 100	−1.0	0.7	−2.3, 0.4	0.15
Country
United States	ref
Canada	−0.2	0.9	−1.5; 2.0	0.79
Western Europe	−0.8	0.9	−2.6; 1.0	0.39
Australia	−0.5	1.9	−4.5; 3.5	0.80
Turkey	−1.1	2.1	−5.4; 3.1	0.58
Korea	0.8	4.1	−7.7; 9.3	0.85
Quality assessment
Low Quality	ref
High Quality	−0.4	0.7	−1.8; 1.0	0.58

ISSN: 1471-2407