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Table 2 Pilot studies on novel techniques for pre-operative non-invasive detection of melanoma metastases in lymph nodes

From: Gamma probe and ultrasound guided fine needle aspiration cytology of the sentinel node (GULF) trial - overview of the literature, pilot and study protocol

Author, yr

Topic

No. of patients

Technique

Sens (%)

Spec (%)

Hinz [72], 2013

Elastography

36

US + power Doppler:

81

76

Elastography:

91

76

Combined:

95

76

Ogata [35], 2014

Elastography

12

US:

77

57

Elastography:

100

71

Stoffels [37], 2015

MSOT and indocyanin green

20

MSOT

100

48.6

  1. Overview of pilot studies investigating non-invasive detection of melanoma lymph node metastases
  2. Abbreviations: yr. year, Sens sensitivity, Spec specificity, US ultrasound, MSOT multispectral optoacoustic tomography