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Table 2 Characteristics and correlation with sarcopenia in 89 patients undergoing radical cystectomy

From: Clinical impact of postoperative loss in psoas major muscle and nutrition index after radical cystectomy for patients with urothelial carcinoma of the bladder

Variables

Total cases, n (%)

Non-sarcopenia, n (%)†

Sarcopenia, n (%)

P value ¶

Total cases

89 (100%)

67 (75%)

22 (25%)

-

Age at RC (year-old), median (IQR)

71 (48–83)

72 (66–75)

71 (62–76)

0.22

BMI (Kg/m2), median (IQR)

22.7 (20.9–24.7)

23.3 (21.6–24.75)

21.8 (19.3–23.0)

0.013

Sex

   

0.16

 Male

70 (79%)

55 (82%)

15 (68%)

 

 Female

19 (21%)

12 (18%)

7 (32%)

 

ECOG-PS

   

1.0

 0

82 (92%)

62 (93%)

20 (91%)

 

  ≥ 1

7 (8%)

5 (7%)

2 (9%)

 

Clinical T category

   

0.007

 NMIBC

6 (7%)

2 (3%)

4 (18%)

 

 T2

42 (47%)

36 (54%)

6 (27%)

 

 T3

19 (21%)

16 (24%)

3 (14%)

 

 T4

22 (25%)

13 (19%)

9 (41%)

 

Clinical N category

   

0.83

 0

78 (88%)

59 (88%)

19 (86%)

 

  ≥ 1

11 (12%)

8 (12%)

3 (14%)

 

Variant histology

   

0.21

 No

68 (76%)

49 (73%)

19 (86%)

 

 Yes

21 (24%)

18 (27%)

3 (14%)

 

Preoeprative nutrition index, median (IQR)

 PNI

47.0 (43.5–50.2)

47.5 (44.0–51.0)

45.2 (38.8–48.6)

0.08

 CONUT score

2 (1–3)

2 (1–3)

2 (1–3)

0.30

Preoeprative blood level, median (IQR)

 Hb (g/dL)

11.2 (10.2–12.7)

11.6 (10.4–12.7)

10.8 (9.8–12.1)

0.07

 CRP (mg/dL)

0.2 (0.1–0.7)

0.2 (0.1–0.6)

0.4 (0.1–1.7)

0.20

 Albumin (g/dL)

4.0 (3.7–4.2)

4.0 (3.8–4.2)

3.9 (3.6–4.2)

0.47

 Sodium (mEq/L)

141 (139–143)

141 (139–143)

140 (138–143)

0.09

 LDH (U/L)

180 (159–201)

180 (159–201)

181 (139–205)

0.54

Neoadjuvant chemotherapy

   

0.23

 No

52 (58%)

38 (57%)

14 (64%)

 

 Yes

37 (42%)

29 (43%)

8 (36%)

 

Adjuvant chemotherapy

   

0.42

 No

75 (84%)

56 (84%)

19 (86%)

 

 Yes

14 (16%)

11 (16%)

3 (14%)

 
  1. RC radical cystectomy; IQR interquartile range; ECOG-PS Eastern Cooperative Oncology Group-Performance Status, NMIBC non-muscle invasive bladder cancer (T1/isolated Tis), BMI body mass index, PNI prognostic nutritional index, CONUT controlling nutritional status, Hb hemoglobin, CRP C-reactive protein LDH lactate dehydrogenase
  2. According to the definition for the Martin's definition [21]
  3. ¶ Comparison between non-sarcopenia cases and sarcopenia cases female with Mann-Whitney U test or chi-squared test