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Table 5 Univariate and multivariate survival analyses of stage ypII RC patients who received Pre-RT

From: Negative lymph node count is an independent prognostic factor for patients with rectal cancer who received preoperative radiotherapy

Characteristic

5-year CCS

Univariate analysis

Multivariate analysis

χ2 test

P

HR(95%CI)

P

Year of diagnosis

 

0.255

0.614

NI

 2004–2007

84.1%

    

 2008–2010

84.7%

    

Sex

 

1.414

0.234

NI

 Male

85.1%

    

 Female

83.0%

    

Age

 

21.435

0.000

 

0.000

 < 60

87.2%

  

Ref

 

 ≥ 60

81.1%

  

0.677 (0.566 ~ 0.810)

0.000

Race

 

1.812

0.404

NI

 White

84.6%

    

 Black

81.4%

    

 Others

84.4%

    

Grade

 

24.552

0.000

 

0.000

 Grade I/ II

85.6%

  

Ref

 

 Grade III/ IV

76.2%

  

0.599 (0.479 ~ 0.748)

0.000

Histologic type

 

6.705

0.035

 

0.042

 Adenocarcinoma

85.0%

  

Ref

 

 Mucinous adenocarcinoma

75.9%

  

0.786 (0.249 ~ 2.481)

0.682

 Signet ring cell carcinoma

71.6%

  

1.103 (0.339 ~ 3.590)

0.871

ypT stage

 

21.301

0.000

 

0.000

 3

85.4%

  

Ref

 

 4

73.2%

  

0.591 (0.445 ~ 0.767)

0.000

LNs

 

9.648

0.002

 

0.892

 ≤ 12

82.5%

  

Ref

 

 > 12

86.7%

  

0.983 (0.749 ~ 1.289)

0.900

NLN

 

20.806

0.000

 

0.002

 ≤ 9

80.9%

  

Ref

 

 > 9

86.5%

  

1.520 (1.170 ~ 1.975)

0.002