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Table 3 Univariate and multivariate survival analyses of RC patients who received Pre-RT

From: Negative lymph node count is an independent prognostic factor for patients with rectal cancer who received preoperative radiotherapy

Characteristic

5-year CCS

Univariate analysis

Multivariate analysis

χ2 test

P

HR(95%CI)

P

Year of diagnosis

 

2.412

0.120

NI

 2004–2007

78.4%

    

 2008–2010

80.2%

    

Sex

 

1.655

0.198

NI

 Male

29.5%

    

 Female

78.4%

    

Age

 

21.805

0.000

 

0.000

 < 60

81.3%

  

Ref

 

 ≥ 60

76.4%

  

0.777 (0.697 ~ 0.866)

0.000

Race

 

14.873

0.000

 

0.909

 White

79.5%

  

Ref

 

 Black

72.7%

  

1.129 (0.937 ~ 1.364)

0.202

 Others

81.8%

  

1.585 (1.246 ~ 2.017)

0.000

Grade

 

112.363

0.000

 

0.000

 Grade I/ II

81.5%

  

Ref

 

 Grade III/ IV

66.9%

  

0.596 (0.523 ~ 0.680)

0.000

Histologic type

 

81.128

0.000

 

0.000

 Adenocarcinoma

80.4%

  

Ref

 

 Mucinous adenocarcinoma

69.2%

  

0.412 (0.308 ~ 0.635)

0.000

 Signet ring cell carcinoma

32.5%

  

0.601 (0.408 ~ 0.885)

0.010

ypT stage

 

148.323

0.000

 

0.000

 1

88.6%

  

Ref

 

 2

87.9%

  

0.293 (0.212 ~ 0.405)

0.000

 3

77.9%

  

0.303 (0.239 ~ 0.384)

0.000

 4

62.6%

  

0.584 (0.494 ~ 0.692)

0.000

LNs

 

2.234

0.135

NI

 ≤ 12

78.5%

    

 > 12

79.8%

    

NLN

 

78.060

0.000

 

0.000

 ≤ 9

74.3%

  

Ref

 

 > 9

82.8%

  

1.623 (1.457 ~ 1.809)

0.000