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Fig. 6 | BMC Cancer

Fig. 6

From: Neural Wiskott-Aldrich syndrome protein (nWASP) is implicated in human lung cancer invasion

Fig. 6

In vitro effect of wiskostatin on A-549 and SK-MES-1 invasion, adhesion, motility and migration. a Wiskostatin treatment impairs the ability of A-549 and SK-MES-1 to adhere to a Matrigel basement membrane over a 25 min period although only with significance in the former cell line. b From cytodex-2 motility assays, A-549 cell motility found to be significantly impaired by wiskostatin treatment but SK-MES-1 motility is not significantly affected. c The rate of closure of a scratch wound is reduced in A-549 cells following wiskostatin treatment but no significant effect on the rate of migration is seen in SK-MES-1 cells. d The capacity of A-549 and SK-MES-1 cells to invade through pores on a Matrigel lined insert is impaired by wiskostatin treatment but only significantly in SK-MES-1 cells

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