Fig. 4
From: Neural Wiskott-Aldrich syndrome protein (nWASP) is implicated in human lung cancer invasion
The effect of wiskostatin and nWASP knockdown on cell behaviour monitored using ECIS. a Wiskostatin treatment significantly increases the capacitance of A-549 cells following seeding. b No significant effect is detected following wounding in A-549 cells. c nWASP knockdown causes a significant increase in capacitance following an electrical wounding. d Wiskostatin also causes a significant increase in capacitance following seeding in SK-MES-1 cells. e A significant increase in capacitance is also detected in SK-MES-1 cells following an electrical wounding in wiskostatin treated cells. f This increase in capacitance is also shown in SK-MES-1 nWASP knockdown cells. g PCR using A-549 and SK-MES-1 nWASP knockdown cells following ECIS demonstrates that decreased nWASP expression in siRNA treated cells is still present at 96 h compared with cells treated with the non-targeting control siRNA. Significant differences between samples are represented by * (P < 0.05), etc. over the appropriate time-points