Table 3 Results of the meta-analysis
Number of studies | Number of patients | HR (95% CI) | Heterogeneity (I2, χ2, P) | |
|---|---|---|---|---|
Overall survival | ||||
All | 8 | 1119 | 1.68 (1.10–2.59)a | 67.0%, 21.21, 0.003 |
Univariate analysis | 4 | 479 | 1.13 (0.85–1.51) | 54.1%, 6.54, 0.088 |
Multivariate analysis | 4 | 640 | 2.37 (1.60–3.49) | 47.3%, 5.69, 0.128 |
Country | ||||
Asian | 3 | 468 | 1.50 (0.61–3.68)a | 80.4%, 10.21, 0.006 |
Western | 5 | 651 | 1.80 (1.33–2.45) | 43.2%, 7.04, 0.134 |
Disease-free survival | ||||
All | 7 | 859 | 1.11 (1.03–1.19) | 33.0%, 8.96, 0.176 |
Univariate analysis | 4 | 377 | 0.86 (0.60–1.24) | 0.0%, 2.18, 0.536 |
Multivariate analysis | 3 | 482 | 1.12 (1.04–1.21) | 59.4%, 4.92, 0.085 |
Country | ||||
Asian | 3 | 554 | 1.42 (0.61–3.31)a | 71.6%, 7.04, 0.030 |
Western | 4 | 305 | 1.11 (1.03–1.20) | 0.0%, 1.56, 0.667 |