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Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity

  • C. P. Baburajeev1,
  • Chakrabhavi Dhananjaya Mohan2, 3,
  • Shobith Rangappa4,
  • Daniel J. Mason5,
  • Julian E. Fuchs5,
  • Andreas Bender5,
  • Uri Barash6,
  • Israel Vlodavsky6Email author,
  • Basappa1Email author and
  • Kanchugarakoppal S. Rangappa2Email author
Contributed equally
BMC Cancer201717:235

https://doi.org/10.1186/s12885-017-3214-8

Received: 25 February 2016

Accepted: 22 March 2017

Published: 31 March 2017

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
25 Feb 2016 Submitted Original manuscript
27 Apr 2016 Reviewed Reviewer Report - Lingegowda Selanere Mangala
15 Jul 2016 Reviewed Reviewer Report - Yong-Hua Yang
26 Jul 2016 Reviewed Reviewer Report - Giuseppe Giannini
20 Oct 2016 Author responded Author comments - Salundi Basappa
Resubmission - Version 2
20 Oct 2016 Submitted Manuscript version 2
6 Feb 2017 Author responded Author comments - Salundi Basappa
Resubmission - Version 3
6 Feb 2017 Submitted Manuscript version 3
8 Mar 2017 Author responded Author comments - CP Baburajeev
Resubmission - Version 4
8 Mar 2017 Submitted Manuscript version 4
14 Mar 2017 Author responded Author comments - CP Baburajeev
Resubmission - Version 5
14 Mar 2017 Submitted Manuscript version 5
Publishing
22 Mar 2017 Editorially accepted
31 Mar 2017 Article published 10.1186/s12885-017-3214-8

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Laboratory of Chemical Biology, Department of Chemistry, Bangalore University
(2)
Department of Studies in Chemistry, University of Mysore
(3)
Department of Studies in Molecular Biology, University of Mysore
(4)
Adichunchanagiri Institute for Molecular Medicine, BG Nagara
(5)
Centre for Molecular Informatics, Department of Chemistry, University of Cambridge
(6)
Cancer and Vascular Biology Research Center, the Bruce Rappaport Faculty of Medicine

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