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Fig. 3 | BMC Cancer

Fig. 3

From: Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity

Fig. 3

Effect of DTP on LLC cell migration and Invasion. LLC cells were plated on BD BioCoat™ chambers (BD Biosciences) and cell migration (without Matrigel coat) (a) and invasion (with Matrigel coat) (b) were measured as described in ‘Methods’. The effect of lead compound DTP (1–10 μM) or heparin (100 μg/mL) on cell migration and invasion is demonstrated by representative photomicrographs (magnification: ×10) and the respective bar graphs. Data are represented as mean ± S.E. *P < 0.1; **P < 0.05. ***P < 0.01

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