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Table 1 Distribution of breast cancer patients according to the immunohistochemical cancer phenotype

From: Distribution of Ki-67 values within HER2 & ER/PgR expression variants of ductal breast cancers as a potential link between IHC features and breast cancer biology

ER/PgR expression

HER2 phenotypes

Breast cancer type

Number of patients

Total

Binary classification

semiquantitative expression

Ki-67 < =20%

Ki-67 > 20%

ER + PgR+

“negative”

0+

Luminal A/B1

248

90

338

1+

165

68

233

2+

44

19

63

“overexpressed”

3+

Luminal B2

82

83

165

Total of patients with ER & PgR positive tumors

539

260

799

ER + PgR-

“negative”

0+

Luminal A/B1

15

10

25

1+

14

12

26

2+

4

3

7

“overexpressed”

3+

Luminal B2

13

20

33

Total of patients with ER positive & PgR negative tumors

46

45

91

ER-PgR+

“negative”

0+

Luminal A/B1

1

3

4

1+

3

2

5

2+

2

0

2

“overexpressed”

3+

Luminal B2

0

0

0

Total of patients with ER negative & PgR positive tumors

6

5

11

ER-PgR-

“negative”

0+

triple-negative

20

86

106

1+

9

31

40

2+

2

6

8

“overexpressed”

3+

pure HER2

27

98

125

Total of patients with ER & PgR negative tumors

58

221

279

Total of all patients

649

531

1180