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Table 2 Methodological features of studies

From: A systematic review of prognostic factors at the end of life for people with a hematological malignancy

Author, Year, Country

Design

Sample characteristics

Hem malig

N

Analysis

Quality rating (QUIPS)

Rabe et al., (2004)

Germany [41]

Retro

Admitted to ICU, with pulmonary infiltrates, requiring ventilation

AML

30

Uni

-

Mod

Soubani et al., (2004)

USA [30]

Retro

Admitted to ICU

HSCT

85

Uni

Multi

Mod

BaHammam et al. (2005)

Saudi Arabia [51]

Retro

Admitted to ICU

All

44

Uni

-

Mod

Owczuk et al., (2005)

Poland [37]

Retro

Admitted to ICU, requiring ventilation

HSCT

40

Uni

Multi

Mod

Naeem et al., (2006)

USA [34]

Retro

Admitted to ICU

Cord HSCT

44

Uni

-

Mod

Ferra et al., (2006)

Spain [46]

Retro

Admitted to ICU

All

100

Uni

Multi

Mod

Lim et al., (2007)

UK [33]

Retro

Admitted to ICU

All

55

Uni

-

Mod

Yang et al., (2007)

Taiwan [31]

Retro

Admitted to ICU, requiring ventilation

HSCT

41

Uni

-

Mod

Nishida & Palalay, (2008)

USA [36]

Retro

Admitted to ICU, requiring ventilation

All

37

Uni

-

Mod

Park et al., (2008)

Korea [38]

Retro

Admitted to ICU for septic shock

Acute leuk

50

Uni

Multi

High

Chen et al., (2009)

Taiwan [54]

Retro

Intracranial hemorrhage (in-patient acute setting)

AML

51

Uni

Multi

High

Hampshire et al., (2009)

UK [48]

Retro

Admitted to ICU (multi-centre)

All

7689

-

Multi

Mod

des Ordons et al., (2010)

USA [44]

Retro

Admitted to ICU

AML

45

Uni

-

High

Burghi et al., (2011)

France [53]

Retro

Admitted to ICU, invasive pulmonary aspergillosis, ventilated

All

67

Uni

Multi

High

Depuydt et al., (2011)

Belgium [43]

Pro

Admitted to ICU

Allo

HSCT

44

Uni

Multi

Mod

Geerse et al., (2011)

Netherlands [47]

Retro

Admitted to ICU

All

86

Uni

Multi

Mod

Park et al., (2011)

Korea [39]

Retro

Admitted to ICU, with AKI, requiring RRT

All

94

Uni

Multi

Mod

Ramos et al., (2011)

USA [55]

Retro

Invasive aspergillosis (in-patient acute setting)

HSCT

449

Uni

Multi

Mod

Agarwal et al. (2012)

Australia [50]

Retro

Admitted to ICU

HSCT

146

Uni

Multi

High

Ferra et al., (2012)

Spain [45]

Retro

Admitted to ICU

Lymphoma

48

Uni

Multi

Low

Hill et al., (2012)

UK [49]

Retro

Admitted to ICU (multi-centre)

All

147

Uni

Multi

Mod

Yeo et al., (2012)

Korea [32]

Retro

Admitted to ICU

All

227

Uni

Multi

Mod

Corbett et al., (2013)

Australia [56]

Retro

Referred to specialist palliative care service (in-pt. & out-pt. setting)

All

276

-

Multi

Mod

de Montmollin et al., (2013)

France [42]

Retro

Admitted to ICU, with septic shock, pulmonary origin (multi-centre)

All

218

Uni

Multi

Mod

Namendys-Silva et al., (2013)

Mexico [35]

Pro

Admitted to ICU

All

102

Uni

Multi

Mod

Price et al., (2013)

USA [40]

Retro

Admitted to ICU, requiring ventilation

Acute leuk

167

Uni

Multi

Mod

Kripp et al., (2014)

Germany [57]

Pros

Admitted to palliative care unit

All

290

Uni

Multi

Mod

Boyaci et al., (2014)

Turkey [52]

Retro

Admitted to ICU

HSCT

48

Uni

Multi

Mod

  1. AML acute myeloid leukemia, ICU intensive care unit, HSCT hematopoietic stem cell transplant (allogeneic and autologous), HM hematological malignancy, Cord HSCT umbilical cord (source of stem cells) hematopoietic stem cell transplant, alloHSCT allogeneic hematopoietic stem cell transplant, AKI acute kidney injury, RRT renal replacement therapy, HIV + ve human immunodeficiency virus positive, U univariate statistical analysis / M - multi- multivariable statistical analysis