Characteristics of early-onset hematotoxicity of sunitinib in Japanese patients with renal cell carcinoma

BMC Cancer

Table 4 Laboratory data during the first cycle

	Group	Baseline	p	Day 7	p	Day 14	p	Day 21	p	Day 28	p	Day 42	p
Lymphocyte count ×10³ /μL	Dose-reduced	1.2 ± 0.6	0.08	1.3 ± 0.1	0.14	0.9 ± 0.1	<0.01	0.9 ± 0.1	0.17	1.1 ± 0.1	0.17	1.2 ± 0.1	0.68
Lymphocyte count ×10³ /μL	Dose-maintained	1.4 ± 0.1	0.08	1.6 ± 0.1	0.14	1.4 ± 0.1	<0.01	1.2 ± 0.2	0.17	1.2 ± 0.1	0.17	1.3 ± 0.1	0.68
Platelet count ×10⁴ /μL	Dose-reduced	30.1 ± 2.0	0.80	26.8 ± 2.0	0.89	15.9 ± 1.2	0.04	12.0 ± 1.4	0.17	16.8 ± 1.8	0.01	24.1 ± 1.9	0.28
Platelet count ×10⁴ /μL	Dose-maintained	30.9 ± 2.6	0.80	27.3 ± 3.1	0.89	22.0 ± 2.4	0.04	15.6 ± 2.1	0.17	11.6 ± 1.0	0.01	20.8 ± 2.3	0.28

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