Fig. 8
Effects of 500 mg/kg*BW 2250 on the subcutaneous tumor growth in nude mice in vivo. Nude mice with tumors of MiaPaca-2 (a), Panc-TuI (c) or patient tissue (b, d) were incubated with 2250 (500 mg/kg*BW) and ddH2O (control) for up to 3 weeks. The tumor volume was measured on alternating days for up to 3 weeks. Asterisk symbols indicate differences between control and 2250 treatment. *** p ≤ 0.001, ** p ≤ 0.01, * p ≤ 0.05, n.s. p >0.05 (one-way ANOVA followed by Tukey’s post-hoc test)