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Fig. 1 | BMC Cancer

Fig. 1

From: Down-regulated expression of OPCML predicts an unfavorable prognosis and promotes disease progression in human gastric cancer

Fig. 1

OPCML expression and its association with prognosis in gastric cancer. (a) Immunohistochemical images of OPCML protein expression in gastric cancer tissues and normal stomach tissues. The reduced expression of OPCML protein in cancerous tissues compared with adjacent non-cancerous tissues (A1, upper-left panel). OPCML protein expression was expressed in normal stomach tissues (A2, upper-right panel) and significantly down-regulated or lost in well-differentiated (A3, lower-left panel) and poorly-differentiated (A4, lower-right panel) tissues. (b) The significant reduction of OPCML protein expression in gastric cancer tissues as compared to the adjacent non-cancerous tissues by immnunohistochemistry (P < 0.001, n = 30). (c) Overall survival in patients with gastric cancer concerning OPCML expression. Kaplan–Meier curves displaying overall survival of patients stratified for OPCML expression. P value was calculated according to a log-rank test. AN:adjacent normal tissues; GC: gastric cancer tissues

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