Fig. 6
From: YBX1 gene silencing inhibits migratory and invasive potential via CORO1C in breast cancer in vitro
CORO1C is an indirect target of YB-1. a Gaussia luciferase reporter assay revealed no significant difference in the average relative luminescence signal (RLU) between cells co-transfected with CORO1C promoter construct and siNeg or siYB-1 cells. b Gaussia luciferase reporter assay showed no significant difference in average RLU between the cells co-transfected with CORO1C promoter construct and YB-1 ORF plasmid or empty vector backbone. These results indicate that YB-1 does not bind directly to the CORO1C promoter. Error bar = SEM, **p < 0.01, ***p < 0.001, indicates statistically significant difference