Table 2 ctDNA and tumor markers measurements in 8 breast cancer patients with stage IV disease
Patient | Tracked mutation | Sample | Target/Total | mutated copies/mL | CA 15.3 (U/ml) | CEA (ng/ml) | Figure |
|---|---|---|---|---|---|---|---|
25 | H1047R | March 07 2014 | 18.36% | 54398 | 97 | 27 | Additional file 4: Figure S1 |
Oct 13 2014 | 0.11% | 12.1 | 32.8 | 7.1 | |||
Nov 03 2014 | 0% | 0 | 32.3 | 7.5 | |||
44 | H1047R | Aug 29 2014 | 1.78% | 310.5 | 126 | 1.6 | Fig. 1b |
Sep 17 2014 | 1.85% | 975 | 997.2 | 5.2 | |||
Oct 23 2014 | 2.08% | 1203.2 | 1219 | 11.6 | |||
Nov 19 2014 | 0.81% | 102.9 | 487.3 | 4.8 | |||
15 | H1047R | Feb 18 2014 | 0.36% | 24.7 | 68.9 | 4.7 | Additional file 4: Figure S3 |
May 29 2014 | 0.32% | 30.6 | 58.6 | 4.3 | |||
Aug 27 2014 | 0.03% | 25.6 | 39.4 | 3.3 | |||
2 | H1047R | Dec 03 2013 | 2.39% | 149.6 | 96.8 | 5.7 | Fig. 1a |
Jan 02 2014 | 3.93% | 77.3 | 91.6 | 12.7 | |||
Jan 30 2014 | 4.39% | 3082.1 | 100.6 | 13.9 | |||
March 03 2014 | 9.61% | 3629.3 | 138.1 | 19.8 | |||
31 | H1047R | March 27 2014 | 0.19% | 13.5 | 89.3 | 22.1 | Fig. 1c |
Aug 29 2014 | 0% | 0 | 30.7 | 6.2 | |||
Oct 02 2014 | 0% | 0 | 28.8 | 5.1 | |||
Nov 03 2014 | 0% | 0 | 17.5 | 4.4 | |||
11 | E545K | March 06 2014 | 27.19% | 9274.2 | 86 | 108 | Additional file 4: Figure S2 |
April 09 2014 | 6.61% | 235.9 | 66 | 86 | |||
3 | E545K | Dec 02 2013 | 4.23% | 412.5 | 57.6 | 2.8 | Fig. 2 |
March 12 2014 | 3.07% | 1839.5 | 60.8 | 3 | |||
Sep 10 2014 | 1.97% | 165.1 | 114.6 | 15.1 | |||
Dec 15 2014 | 0.76% | 143.5 | 179.5 | 9 | |||
6 | E542K | Feb 10 2014 | 0.24% | 63.30 | 115.6 | 3.9 | Additional file 4: Figure S4 |
Apr 04 2014 | 0% | 0 | 88.5 | 2.9 | |||
Sep 05 2014 | 0% | 0 | 45 | 1.7 |