Table 2 HER2,cMet, and FGFR2 statuses in a cohort of GC patients and corresponding PDX donors
Samples | HER2 | cMet | FGFR2 | |||||
|---|---|---|---|---|---|---|---|---|
OP(%) | AP(%) | Positive(%) | OP(%) | AP(%) | AP(%) | |||
IHC3+ | FISH | IHC /FISH | IHC3+ | IHC2+ | IHC3+/2+ | FISH | FISH | |
A cohort of GC patients (n = 163) | 12(7.3%) | 5(3.1%) | 17(10.4%) | 7(4.3%) | 25(15.3%) | 32(19.6%) | 7(4.3%) | 6(3.7%) |
Corresponding patients of PDX models (n = 32) | 3(9.4%) | 1(3.1%) | 4(12.5%) | 3(9.4%) | 5(15.6%) | 8(25.0%) | 3(9.4%) | 1(3.1%) |