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Table 1 Comparison of ROC areas among individual biomarkers

From: Receiver operating characteristic analysis of prediction for gastric cancer development using serum pepsinogen and Helicobacter pylori antibody tests

Outcome (Cut-off value)

ROC area (95% CI)

PG I/II

PG I

PG II

HP

H. pylori infection

0.820 ± 0.023

0.455 ± 0.022

0.186 ± 0.016

-

(HP antibody = 10.0)

(0.774–0.865)

(0.411–0.499)

(0.153–0.217)

H. pylori infection

0.849 ± 0.024

0.478 ± 0.025

0.181 ± 0.018

-

(HP antibody = 5.0)

(0.801–0.896)

(0.429–0.527)

(0.146–0.216)

Gastric cancer

0.649 ± 0.017

0.561 ± 0.011

0.434 ± 0.018

0.574 ± 0.018

 

(0.615–0.683)

(0.526–0.597)

(0.400–0.469)

(0.538–0.610)

  1. HP Helicobacter pylori, PG pepsinogen, ROC receiver operating characteristic, CI confidence interval