Fig. 2
From: miR-124 targets GATA6 to suppress cholangiocarcinoma cell invasion and metastasis
miR-124 inhibits CCA cell invasion and metastasis. a The miR-124 levels in two CCA cell lines, QBC939 and RBE, were lower than those in cultured primary biliary epithelial cells, determined by real-time PCR analysis. b, c Validation of the miR-124 levels after transfection. d The effect of miR-124 overexpression on CCA cell invasion, as shown by Transwell assays in vitro. e The effect of miR-124 overexpression on CCA cell migration according to wound healing assays in vitro. f The effect of miR-124 overexpression on QBC939 cell metastasis following xenotransplantation into nude mice by intrasplenic injection. In-miR-124: CCA cells transfected with miR-124 inhibitors; Ex-miR-124: CCA cells transfected with miR-124 mimics. *P < 0.05