Fig. 4
Antiviral effects mediated by JVRS-100 in chronic WHV infected woodchucks with HCC. Percentage change in serum WHV DNA (a) and WHsAg (b) from pre-treatment level at T0 in woodchucks with pre-existing liver tumors during and following IV treatment with JVRS-100 at concentrations of 100 μg/animal (low dose; n = 3) or 300 μg/animal (high dose; n = 3) or with vehicle (placebo; n = 6) for 12 weeks. Vertical lines denote standard deviations