Skip to main content

Table 1 Drugs, doses and therapeutic regimens applied in the presented studies

From: The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice

Experimental model Drug Route of administration Dose Treatment regimen
Spontaneous tumor formation (Fig. 1) 1-MNA per os in drinking water 100 mg/kg/day continuously from the age of 8 to 12 weeks to the day of the necropsy
1,4-DMP per os in drinking water 100 mg/kg/day continuously from the age of 8 to 12 weeks to the day of the necropsy
PC-3 M-luc2 tumors (Fig. 2) 1,4-DMP per os in drinking water 100 mg/kg/day continuously from the day 1 to the end of the experiment
DTX intraperitoneally 10 mg/kg 2 doses at days 15 and 22