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Fig. 3 | BMC Cancer

Fig. 3

From: The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice

Fig. 3

The influence of the combined treatment comprising the use of docetaxel (DTX) and 1,4-DMP on platelet morphology and activity in BALB/c Nude mice bearing PC-3M-luc2 tumors. a Platelet count; b platelet crit (PCT); c mean platelet volume (MPV); d platelet distribution width (PDW) determined on the last day of the experiment (day 46). Plasma concentration of: e 6-keto-prostaglandin F1α (6-keto-PGF1α) (*p < 0.05 vs. control and 1,4-DMP); f thromboxane B2 (TXB2) (*p < 0.05 vs. control and 1,4-DMP); g soluble P-selectin (*p < 0.05 vs. control and 1,4-DMP); and h von Willebrand Factor (vWF) (*p < 0.05 vs. control and 1,4-DMP), determined on the last day of the experiment (day 46). All data are presented as mean ± SD values

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