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Table 1 Summary of cohort demographics and patient characteristics

From: A novel FOXO1-mediated dedifferentiation blocking role for DKK3 in adrenocortical carcinogenesis

Characteristics

Number of Cases

Percentage

Total Number

38

NA

Gender

 Male

14

35.8%

 Female

24

63.2%

Age ± SD (y)

57.7 ± 13.2

NA

Cohort

 Yale

10

26.3%

 Karolinska

25

65.8%

 Düsseldorf

3

7.9%

Tumor Size (cm)

 Mean ± SD

12.8 ± 4.4

NA

 Range

5.5–21.0

NA

ENSAT 2008 Stage

 I

0

0.0%

 II

18

47.4%

 III

11

28.9%

 IV

9

23.7%

Hormone Hypersecretion

 Aldosterone

1

2.6%

 Cortisol

9

23.7%

 Androgen/DHEA

4

10.5%

 Estrogen

1

2.6%

 Multi-secretinga

5

13.2%

 Non-functional

14

36.8%

 No information available

4

10.5%

Outcome

 Alive, no recurrence

11

28.9%

 Alive, recurrence

5

13.2%

 Death from disease

16

42.1%

 Death from other causes

4

10.5%

 Lost to follow-up

2

5.3%

  1. aTumors secreting two or more of the following hormones: aldosterone, cortisol, testosterone, or DHEA
  2. y years, cm centimeter, SD standard deviation, ENSAT European Network for the Study of Adrenal Tumors, DHEA dehydroepiandrosterone, NA not applicable