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Table 1 Summary of cohort demographics and patient characteristics

From: A novel FOXO1-mediated dedifferentiation blocking role for DKK3 in adrenocortical carcinogenesis

Characteristics Number of Cases Percentage
Total Number 38 NA
Gender
 Male 14 35.8%
 Female 24 63.2%
Age ± SD (y) 57.7 ± 13.2 NA
Cohort
 Yale 10 26.3%
 Karolinska 25 65.8%
 Düsseldorf 3 7.9%
Tumor Size (cm)
 Mean ± SD 12.8 ± 4.4 NA
 Range 5.5–21.0 NA
ENSAT 2008 Stage
 I 0 0.0%
 II 18 47.4%
 III 11 28.9%
 IV 9 23.7%
Hormone Hypersecretion
 Aldosterone 1 2.6%
 Cortisol 9 23.7%
 Androgen/DHEA 4 10.5%
 Estrogen 1 2.6%
 Multi-secretinga 5 13.2%
 Non-functional 14 36.8%
 No information available 4 10.5%
Outcome
 Alive, no recurrence 11 28.9%
 Alive, recurrence 5 13.2%
 Death from disease 16 42.1%
 Death from other causes 4 10.5%
 Lost to follow-up 2 5.3%
  1. aTumors secreting two or more of the following hormones: aldosterone, cortisol, testosterone, or DHEA
  2. y years, cm centimeter, SD standard deviation, ENSAT European Network for the Study of Adrenal Tumors, DHEA dehydroepiandrosterone, NA not applicable