Skip to main content

Table 1 Demographic and clinical characteristics of 538 NSCLC patients

From: A genetic variant in long non-coding RNA MALAT1 associated with survival outcome among patients with advanced lung adenocarcinoma: a survival cohort analysis

Variables

NSCLC Patients n (%)

Deaths n = 328

MST (months)

Log-rank P

Crude HR (95% CI)

Age

 ≤65

253 (0.47)

178

29.9

---

1.00 (Reference)

 >65

285 (0.53)

228

16.4

<0.001

1.54 (1.27–1.88)

Sex

 Male

450 (0.84)

345

20.7

---

1.00 (Reference)

 Female

88 (0.16)

61

28.9

0.042

0.75 (0.57–0.99)

Smoking

 Never

93 (0.17)

65

30.5

---

1.00 (Reference)

 Ever

445 (0.83)

341

21.1

0.11

1.24 (0.95–1.61)

Histology

Adenocarcinoma

237 (0.44)

165

24.5

---

1.00 (Reference)

 Squamous cell carcinoma

188 (0.35)

143

28.1

0.81

1.03 (0.82–1.29)

 Others

113 (0.21)

98

13.3

<0.01

1.74 (1.35–2.23)

Clinical Stage

 Early

140 (0.26)

78

57.6

---

1.00 (Reference)

 Advanced

398 (0.74)

328

17.9

<0.001

2.43 (1.89–3.12)

Surgery

 No

334 (0.62)

281

17.6

---

1.00 (Reference)

 Yes

204 (0.38)

125

36.1

<0.01

0.53 (0.43–0.65)

Chemotherapy

 No

126 (0.23)

95

20.1

---

1.00 (Reference)

 Yes

412 (0.77)

311

23.7

0.24

0.87 (0.69–1.1)

Radiotherapy

 No

291 (0.54)

208

22.9

---

1.00 (Reference)

 Yes

247 (0.46)

198

21.5

0.24

1.08 (0.89–1.31)