Table 2 Summary of mutations identified by melanoma type
From: Validation of an NGS mutation detection panel for melanoma
Melanoma Type | BRAF | NRAS | KRAS | KIT | MEK | GNA11 | GNAQ | WT | Total |
|---|---|---|---|---|---|---|---|---|---|
Cutaneous SSM | 15 | 11 | 0 | 1 | 1 | 0 | 0 | 6 | 34 |
Cutaneous Nodular | 15 | 11 | 0 | 0 | 1 | 0 | 0 | 11 | 38 |
Cutaneous NOS | 12 | 3 | 0 | 1 | 1 | 0 | 0 | 5 | 22 |
LMM | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 5 |
Acral Lentiginous | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 2 | 4 |
Malignant blue naevus | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2 |
Mucosal | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 |
Unknown Primary | 0 | 3 | 0 | 1 | 0 | 0 | 1 | 1 | 6 |
Uveal | 0 | 2 | 0 | 0 | 0 | 4 | 4 | 9 | 19 |
Total | 44 | 33 | 0 | 3 | 4 | 4 | 5 | 39 | 132 |