Skip to main content

Table 1 Summary of TSPYL5 mRNA expression, DNA methylation frequency, protein expression based on Gleason score

From: Testis specific Y-like 5: gene expression, methylation and implications for drug sensitivity in prostate carcinoma

Pathology Age (yrs) GS No of samples mRNAa expression Methylationb frequency (%) IHCc
Normal 40–60 ---- 3 3/3 <10 -
Benign 59–79 ---- 9 7/9 25 -
Adenocarcinoma 36–50 6 4 3/4 28 12
Adenocarcinoma 50–70 7 14 11/14 39 8
Adenocarcinoma 60–68 ≥8 3 0/3 70 0
  1. aPCR analysis of TSPYL5 mRNA expression in benign and prostate adenocarcinoma
  2. bAnalysis of DNA methylation (MSP) in the tissues (n = 3 each). The gel band intensities were quantified by Image J software as noted in methods
  3. cComposite score (CS) is derived from staining intensity times percent positive cells for TSPYL5 protein expression