Fig. 1
From: Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma
AZ and/or MS-275 treatments produced a dose-dependent reduction in NB cells. a-c present graphic and tabulated evidence for the dose response. Doses were AZ(0–160 μM), MS-275(0–3 μM) and AZ + MS-275(0–160 μM + 0.75 μM) for 48 h treatment of NSC6539, NSC6562, SH-SY5Y, SK-N-SH and SK-N-BE(2) cells compared to the untreated group. The greatest decrease in IC50 was observed for AZ + MS-275 combination as follow: SH-SY5Y = 17.5 μM, SK-N-SH = 16.5 μM and SK-N-BE(2) = 19.2 μM