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Fig. 3 | BMC Cancer

Fig. 3

From: Enhanced expression of Vastatin inhibits angiogenesis and prolongs survival in murine orthotopic glioblastoma model

Fig. 3

H1-Vastatin caused angiogenesis inhibition in vivo and decreased microvessel density. a Immunostaining of CD34, a vessel endothelia marker, on brain tumour sections. The CD34+ cell numbers were fewer in the H1-Vastatin treated group than the PBS and H1-EGFP treated groups. b Histogram showing the microvessel density (MVD) in tumours of different treatment groups. Percentage of microvessel endothelial cells in the H1-Vastatin treated group was significant lower than in the PBS and H1-EGFP treated groups. (n = 3; * P < 0.05 against PBS treated group, # P < 0.05 against H1-EGFP treated group)

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BMC Cancer

ISSN: 1471-2407

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