Fig. 2

Administration of H1-Vastatin increased intracranial Vastatin expression and significantly prolonged survival of GB bearing mice. a Bands of Vastatin exclusive PCR products in agarose gel electrophoresis. H1-Vastatin significantly enhanced the mRNA level of Vastatin in the right hemispheres of treated mice, which lasted over 2 weeks. b Survival curves of GB bearing mice (n = 7). H1-Vastatin and H1-Endostatin treatment significantly prolonged the median survival time of GB bearing mice to 75 and 64 days respectively, from 48 and 51 days for the PBS and H1-EGFP treated groups (P < 0.05). There was no significant difference in survival time between H1-Vastatin and H1-Endostatin treated groups