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Table 2 Multivariate analysis for OS and DFS of 90 CRC patients

From: miR-296 inhibits the metastasis and epithelial-mesenchymal transition of colorectal cancer by targeting S100A4

Variables OS DFS
HR 95% CI P HR 95% CI P
Tumor invasion (T1/T2 vs T3/T4) 0.82 (0.33-2.00) 0.658 0.77 (0.31-1.90) 0.567
Lymph node status (<1 vs ≥1) 2.35 (1.25-4.41) 0.008* 2.43 (1.30-4.59) 0.006*
Distant metastasis (Absent vs Present) 7.89 (4.58-13.61) <0.001* 9.41 (5.49-16.16) <0.001*
TNM stage (I/II vs III/IV) 1.61 (1.01-2.59) 0.049* 1.77 (1.10-2.86) 0.019*
miR-296 expression (Low vs High) 0.44 (0.22-0.86) 0.016* 0.43 (0.27-1.02) 0.038*
  1. OS overall survival, DFS disease-free survival, CRC colorectal cancer, TNM tumor-node-metastasis. * Statistically significant