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Table 1 Clinicopathological findings and correlation with miR-296 expression in CRC

From: miR-296 inhibits the metastasis and epithelial-mesenchymal transition of colorectal cancer by targeting S100A4

Features

 

n = 90

miR-296 expression

P

   

Low

High

 

Age (years)

<65

59

30 (50.85%)

29 (49.15%)

0.824

≥65

31

15 (48.39%)

16 (51.61%)

Sex

Male

48

26 (54.17%)

22 (45.83%)

0.398

Female

42

19 (45.24%)

23 (54.76%)

Tumor grade

G1 + G2

67

35 (52.24%)

32 (47.76%)

0.468

G3 + G4

23

10 (43.48%)

13 (56.52%)

Size (cm)

<5

30

17 (56.67%)

13 (43.33%)

0.371

≥5

50

28 (56.00%)

32 (44.00%)

Tumor invasion

T1 + T2

22

5 (22.73%)

17 (77.27%)

0.003*

T3 + T4

68

40 (58.82%)

28 (41.18%)

Lymph node status

<1

48

16 (33.33%)

32 (66.67%)

0.001*

≥1

42

29 (69.05%)

13 (30.95%)

Distant metastasis

Absent

69

30 (43.48%)

39 (56.52%)

0.025*

Present

21

15 (71.43%)

6 (28.57%)

TNM stage

I + II

43

16 (37.21%)

27 (62.79%)

0.020*

III + IV

47

29 (61.70%)

18 (38.30%)

  1. CRC colorectal cancer, TNM tumor-node-metastasis. * Statistically significant