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Fig. 8 | BMC Cancer

Fig. 8

From: miR-296 inhibits the metastasis and epithelial-mesenchymal transition of colorectal cancer by targeting S100A4

Fig. 8

S100A4 knockdown abrogates the effects of miR-296 inhibition on EMT, migration and invasion of CRC cells. a miR-296 silenced SW480 cells that were transfected with S100A4 siRNA and scrambled siRNA (scr siRNA) were subjected to western blot. S100A4 siRNA significantly decreased S100A4 in miR-296 silenced SW480 cells, and led to increased E-cadherin expression and decreased Vimentin expression. b S100A4 knockdown significantly inhibited the migration of miR-296 silenced SW480 cells. c S100A4 knockdown significantly inhibited the migration and invasion of miR-296 silenced SW480 cells. n = 3, *P < 0.05

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BMC Cancer

ISSN: 1471-2407

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