Fig. 7

WDR13 regulates c-Jun function in vivo. Expression analysis of AP1 target genes from proximal colon of indicated genotypes and treatments (excluding tumors). Expression levels were normalized to gapdh. Black bar, Wdr13 ^+/0 mice (n = 2); white bar, Wdr13 ^-/0 mice (n = 2); Dark grey bar, AOM/DSS-treated Wdr13 ^+/0 mice (n = 2); Light grey bar, AOM/DSS-treated Wdr13 ^-/0 mice (n = 3). n- Shows number of mice used in respective genotype. All real time PCR was performed in technical triplicate. Student’s t-test was used for statistical analysis and error bar shows s.e.m