Table 2 Top 50 most differentially expressed annotated genes in H. felis-infected Myd88 −/− mice at 25 weeks compared to uninfected controls
Symbol | Gene Name | LogFC | Adj. P.Val |
|---|---|---|---|
Chil4 | chitinase-like 4 | 5.77 | 4.05E-04 |
Bpifb1 | BPI fold containing family B, member 1 | 4.90 | 1.97E-04 |
Cd74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) | 4.28 | 4.93E-08 |
H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 4.09 | 2.35E-07 |
Ido1 | indoleamine 2,3-dioxygenase 1 | 3.88 | 1.39E-04 |
H2-DMa | histocompatibility 2, class II, locus DMa | 3.34 | 1.29E-05 |
H2-DMb2 | histocompatibility 2, class II, locus Mb2 | 3.33 | 2.22E-06 |
Igtp | interferon gamma induced GTPase | 3.29 | 1.54E-04 |
H2-Eb1 | histocompatibility 2, class II antigen E beta | 3.28 | 2.51E-06 |
Gbp2 | guanylate binding protein 2 | 3.27 | 3.49E-05 |
Sftpd | surfactant associated protein D | 3.26 | 3.73E-07 |
Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 2.92 | 3.46E-06 |
H2-K2 | histocompatibility 2, K region locus 2 | 2.78 | 2.64E-07 |
H2-K1 | histocompatibility 2, K1, K region | 2.64 | 1.04E-06 |
B2m | beta-2 microglobulin | 2.59 | 3.46E-06 |
Pkp4 | plakophilin 4 | 2.54 | 2.04E-06 |
H2-DMb1 | histocompatibility 2, class II, locus Mb1 | 2.52 | 3.46E-06 |
Ubd | ubiquitin D | 2.51 | 2.90E-04 |
H2-Aa | histocompatibility 2, class II antigen A, alpha | 2.47 | 2.15E-05 |
Irgm2 | immunity-related GTPase family M member 2 | 2.42 | 9.04E-05 |
H2-Q7 | histocompatibility 2, Q region locus 7 | 2.32 | 2.22E-06 |
Cxcl9 | chemokine (C-X-C motif) ligand 9 | 2.30 | 6.23E-05 |
Irf1 | interferon regulatory factor 1 | 2.23 | 7.54E-05 |
Serpina3g | serine (or cysteine) peptidase inhibitor, clade A, member 3G | 2.22 | 5.85E-06 |
H2-M2 | histocompatibility 2, M region locus 2 | 2.21 | 5.85E-06 |
Casp1 | caspase 1 | 2.17 | 1.86E-04 |
H2-D1 | histocompatibility 2, D region locus 1 | 2.17 | 1.07E-06 |
Ear2 | eosinophil-associated, ribonuclease A family, member 2 | 2.16 | 6.91E-04 |
H2-T23 | histocompatibility 2, T region locus 23 | 2.07 | 5.85E-06 |
Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 2.05 | 1.54E-04 |
Psmb10 | proteasome (prosome, macropain) subunit, beta type 10 | 2.03 | 5.50E-05 |
Sgk1 | serum/glucocorticoid regulated kinase 1 | −2.01 | 3.48E-04 |
Apoa4 | apolipoprotein A-IV | −2.31 | 2.33E-05 |
Ttr | transthyretin | −2.37 | 2.15E-05 |
Fabp3 | fatty acid binding protein 3, muscle and heart | −2.37 | 1.61E-04 |
Muc5ac | mucin 5, subtypes A and C, tracheobronchial/gastric | −2.41 | 7.14E-04 |
Smim24 | small integral membrane protein 24 | −2.61 | 3.46E-06 |
Lpl | lipoprotein lipase | −2.75 | 8.29E-05 |
Pdia2 | protein disulfide isomerase associated 2 | −3.08 | 3.10E-05 |
Pnliprp1 | pancreatic lipase related protein 1 | −3.18 | 5.76E-04 |
Gm5771 | predicted gene 5771 | −3.36 | 3.53E-04 |
Hamp2 | hepcidin antimicrobial peptide 2 | −3.43 | 1.59E-04 |
Pnliprp2 | pancreatic lipase-related protein 2 | −3.44 | 7.47E-04 |
Rnase1 | ribonuclease, RNase A family, 1 (pancreatic) | −3.78 | 5.55E-04 |
Try5 | trypsin 5 | −4.17 | 7.45E-04 |
Gm5409 | predicted pseudogene 5409 | −4.44 | 4.89E-05 |
Try4 | trypsin 4 | −4.87 | 4.39E-05 |
Try10 | trypsin 10 | −5.08 | 2.69E-06 |
Amy2a5 | amylase 2a5 | −6.44 | 2.22E-06 |
Chia1 | chitinase, acidic 1 | −6.68 | 8.93E-05 |