Clinical performance evaluation of a sensitive, rapid low-throughput test for KRAS mutation analysis using formalin-fixed, paraffin-embedded tissue samples

Table 4 True discordant results at the dichotomous level “mutation detected” versus “no mutation detected” for mutations in exon 2

Sample ID	Idylla™	therascreen	Confirmatory testing	New DNA extraction?
S8251	No mutation detected	12ALA	No mutation detected	Yes
S8261	G13D	No mutation detected	No mutation detected	Yes
S8320	G12R	No mutation detected	No mutation detected	No
S8322	G12V	No mutation detected	G12V	Yes
S8382	G13D	No mutation detected	No mutation detected	Yes
S8505	G13D	No mutation detected	No mutation detected	Yes

Listing of the samples with a true discordant result, namely mutated versus not mutated KRAS. Confirmatory testing of mutational status of the samples are shown in column 3

ISSN: 1471-2407