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Table 2 Proportional hazard model for overall survival and recurrence-free survival prediction

From: Low CCL17 expression associates with unfavorable postoperative prognosis of patients with clear cell renal cell carcinoma

Variables

OS (n = 286)

RFS (n = 262)

HR (95%CI)

P-value†

p-value†

(bootstrap‡)

HR (95%CI)

P-value†

p-value†

(bootstrap‡)

Pathological T stage

 

<0.001

  

<0.001

 

 pT1

Reference

  

Reference

  

 pT2

2.655 (1.361–5.180)

0.004

0.005

2.586 (1.197–5.587)

0.016

0.011

 pT3

2.879 (1.756–4.720)

<0.001

0.001

3.061 (1.795–5.221)

<0.001

0.002

 pT4

3.809 (1.054–14.422)

0.027

0.292

8.842 (2.712–28.823)

<0.001

0.009

Distant metastasis

 Yes vs No

2.467 (1.283–4.744)

0.007

0.073

   

Fuhrman grade

 

0.005

  

0.001

 

 1

Reference

  

Reference

  

 2

1.957 (0.701–5.466)

0.200

0.219

1.439 (0.563–3.674)

0.447

0.490

 3

4.067 (1.353–12.223)

0.012

0.012

4.024 (1.433–11.301)

0.008

0.019

 4

6.786 (1.494–30.828)

0.013

0.002

5.377 (1.258–22.981)

0.023

0.005

Necrosis

 Present vs Absent

2.180 (1.216–3.909)

0.009

0.063

2.191 (1.202–3.991)

0.010

0.018

ECOG PS

 0 vs ≥1

2.123 (1.333–3.382)

0.002

0.004

2.356 (1.426–3.893)

0.001

0.002

CCL17 expression

 High vs Low

0.504 (0.309–0.824)

0.006

0.011

0.448 (0.267–0.751)

0.002

0.025

  1. ECOG PS Eastern Cooperative Oncology Group performance status, HR hazard ratio, CI confidence interval, OS overall survival, RFS recurrence-free survival
  2. P-value < 0.05 was regarded as statistically significant
  3. †Data obtained from the Cox proportional hazards model, ‡Bootstrapping with 1000 resamples were used