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Table 2 Proportional hazard model for overall survival and recurrence-free survival prediction

From: Low CCL17 expression associates with unfavorable postoperative prognosis of patients with clear cell renal cell carcinoma

Variables OS (n = 286) RFS (n = 262)
HR (95%CI) P-value† p-value† (bootstrap‡) HR (95%CI) P-value† p-value† (bootstrap‡)
Pathological T stage   <0.001    <0.001  
 pT1 Reference    Reference   
 pT2 2.655 (1.361–5.180) 0.004 0.005 2.586 (1.197–5.587) 0.016 0.011
 pT3 2.879 (1.756–4.720) <0.001 0.001 3.061 (1.795–5.221) <0.001 0.002
 pT4 3.809 (1.054–14.422) 0.027 0.292 8.842 (2.712–28.823) <0.001 0.009
Distant metastasis
 Yes vs No 2.467 (1.283–4.744) 0.007 0.073    
Fuhrman grade   0.005    0.001  
 1 Reference    Reference   
 2 1.957 (0.701–5.466) 0.200 0.219 1.439 (0.563–3.674) 0.447 0.490
 3 4.067 (1.353–12.223) 0.012 0.012 4.024 (1.433–11.301) 0.008 0.019
 4 6.786 (1.494–30.828) 0.013 0.002 5.377 (1.258–22.981) 0.023 0.005
Necrosis
 Present vs Absent 2.180 (1.216–3.909) 0.009 0.063 2.191 (1.202–3.991) 0.010 0.018
ECOG PS
 0 vs ≥1 2.123 (1.333–3.382) 0.002 0.004 2.356 (1.426–3.893) 0.001 0.002
CCL17 expression
 High vs Low 0.504 (0.309–0.824) 0.006 0.011 0.448 (0.267–0.751) 0.002 0.025
  1. ECOG PS Eastern Cooperative Oncology Group performance status, HR hazard ratio, CI confidence interval, OS overall survival, RFS recurrence-free survival
  2. P-value < 0.05 was regarded as statistically significant
  3. †Data obtained from the Cox proportional hazards model, ‡Bootstrapping with 1000 resamples were used