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Table 2 Poisson regression analysis results for diagnosis for thyroid cancer

From: Thyroid fine-needle aspiration biopsy positively correlates with increased diagnosis of thyroid cancer in South Korean patients

Variables Total patients Patients with thyroid fine-needle aspiration biopsy
RRa 95% CI P-value RRa 95% CI P-value
Regional variables
 Number of thyroid fine-needle aspiration biopsy in Si-Gun-Gu (per 100,000 people; per 100 increase) 1.108 1.090 1.126 <0.0001 0.973 0.952 0.995 0.0143
 Financial independence rate of local government (per 10%) 1.037 0.955 1.125 0.3849 1.003 0.992 1.015 0.5599
Individual variables
 Sex
  Male 0.206 0.194 0.220 <0.0001 1.075 0.990 1.168 0.0852
  Female 1.000 - - - 1.000 - - -
 Age (years)
  0–19 0.059 0.038 0.093 <0.0001 1.359 0.703 2.627 0.3613
  20–29 1.155 0.864 1.543 0.3313 1.700 1.065 2.713 0.0263
  30–39 3.334 2.532 4.391 <0.0001 1.796 1.142 2.824 0.0113
  40–49 5.389 4.100 7.082 <0.0001 1.519 0.968 2.385 0.0689
  50–59 6.430 4.892 8.450 <0.0001 1.219 0.776 1.913 0.3897
  60–69 4.721 3.578 6.230 <0.0001 0.921 0.584 1.453 0.7245
  70–79 2.542 1.901 3.398 <0.0001 0.858 0.535 1.376 0.5248
  80+ 1.000 - - - 1.000 - - -
 Type of insurance coverage
  Medical Aid 0.768 0.642 0.919 0.0040 1.466 1.101 1.952 0.0087
  NHI (self-employed) 0.785 0.745 0.827 <0.0001 1.014 0.947 1.085 0.6984
  NHI (employed) 1.000 - - - 1.000 - - -
 Income (percentiles)
  0–29% 0.640 0.591 0.692 <0.0001 0.879 0.794 0.974 0.0135
  30–59% 0.725 0.682 0.771 <0.0001 0.965 0.892 1.045 0.3839
  60%+ 1.000 - - - 1.000 - - -
 Year
  2003 1.000 - - - 1.000 - - -
  2004 0.853 0.727 1.001 0.0517 0.784 0.597 1.029 0.0795
  2005 0.907 0.776 1.060 0.2187 0.770 0.593 1.000 0.0500
  2006 1.029 0.885 1.197 0.7092 0.878 0.686 1.125 0.3051
  2007 1.258 1.086 1.456 0.0022 0.924 0.727 1.174 0.5179
  2008 1.438 1.243 1.664 <0.0001 0.927 0.730 1.178 0.5372
  2009 1.765 1.530 2.035 <0.0001 1.023 0.807 1.297 0.8505
  2010 1.583 1.361 1.842 <0.0001 0.870 0.680 1.112 0.2646
  2011 1.757 1.509 2.045 <0.0001 1.026 0.804 1.309 0.8379
  2012 1.725 1.477 2.015 <0.0001 1.041 0.813 1.332 0.7510
  2013 1.579 1.345 1.854 <0.0001 1.067 0.830 1.371 0.6152
 Region (distance from Seoul)
  Gangwon-do (100.6 km) 1.001 0.662 1.515 0.9960 0.999 0.557 1.789 0.9959
  Gyeonggi-do (40.0 km) 1.192 1.042 1.364 0.0107 0.955 0.792 1.151 0.6277
  Gyeongsangnam-do (366.4 km) 1.234 0.925 1.647 0.1526 1.130 0.760 1.680 0.5457
  Gyeongsangbuk-do (225.5 km) 1.293 0.882 1.897 0.1879 1.322 0.777 2.249 0.3028
  Gwangju (295.3 km) 1.435 1.124 1.832 0.0037 0.882 0.634 1.226 0.4537
  Daegu (288.3 km) 1.325 1.099 1.598 0.0032 1.106 0.850 1.437 0.4539
  Daejeon (160.9 km) 1.735 1.451 2.075 <0.0001 1.445 1.130 1.848 0.0033
  Busan (394.2 km) 1.048 0.883 1.244 0.5927 1.238 0.974 1.574 0.0810
  Seoul 1.238 1.003 1.528 0.0468 1.038 0.776 1.388 0.7999
  Ulsan (395.7 km) 1.354 1.121 1.636 0.0017 1.370 1.074 1.746 0.0111
  Incheon (37.7 km) 1.000 - - -     
  Jeollanam-do (346.3 km) 1.774 1.150 2.737 0.0095 1.387 0.751 2.562 0.2954
  Jeollabuk-do (216.9 km) 1.398 0.924 2.113 0.1125 1.263 0.710 2.245 0.4275
  Jeju-do (541.6 km) 1.535 0.996 2.366 0.0522 1.436 0.794 2.598 0.2315
  Chungcheongnam-do (129.9 km) 1.383 0.982 1.946 0.0633 1.239 0.772 1.990 0.3746
  Chungcheongbuk-do (137.1 km) 1.130 0.780 1.636 0.5188 0.960 0.564 1.634 0.8805
 QIC 99756.63 24319.41
  1. aRelative risk for diagnosis of thyroid cancer, based on the results of Poisson regression analysis with GEE adjusted for individual- and regional-level characteristic to identify the relationship between regional thyroid fine-needle biopsy rates and diagnosis of thyroid cancer