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Table 1 Distribution of person-years by diagnosis of thyroid cancer

From: Thyroid fine-needle aspiration biopsy positively correlates with increased diagnosis of thyroid cancer in South Korean patients

Variables Total patients Patients with thyroid fine-needle aspiration biopsy
  Diagnosed None P-value Diagnosed None P-value
  N/Mean %/SD N/Mean %/SD   N/Mean %/SD N/Mean %/SD  
Regional variables
 Number of thyroid fine-needle aspiration biopsies in Si-Gun-Gu (per 100,000 people) 348.2 225.0 253.3 207.9 <0.0001a 348.2 225.0 425.9 236.8 <.0001a
 Financial independence rate of local government (%) 62.2 23.3 62.4 23.6 0.5344a 62.2 23.3 59.4 22.9 <.0001a
Individual variables
 Sex
  Male 1140 0.02 5,514,264 99.98 <0.0001b 1140 22.04 4033 77.96 0.1968b
  Female 5479 0.10 5,503,665 99.90   5479 21.23 20,327 78.77
 Age (years)
  0–19 30 0.00 2,622,533 100.00 <0.0001b 30 21.58 109 78.42 <0.0001b
  20–29 339 0.02 1,580,567 99.98   339 26.26 952 73.74
  30–39 1210 0.07 1,866,884 99.94   1210 26.86 3295 73.14
  40–49 1972 0.10 1,909,614 99.90   1972 23.69 6352 76.31
  50–59 1819 0.13 1,392,449 99.87   1819 19.48 7519 80.52
  60–69 876 0.10 894,668 99.90   876 16.65 4386 83.35
  70–79 320 0.06 543,227 99.94   320 16.82 1582 83.18
  80+ 53 0.03 207,987 99.98   53 24.31 165 75.69
 Type of insurance coverage
  Medical Aid 144 0.04 383,596 99.96 <0.0001b 144 34.37 275 65.63 <0.0001b
  NHI (self-employed) 2142 0.05 4,060,517 99.95   2142 21.69 7734 78.31
  NHI (employed) 4333 0.07 6,573,816 99.93   4333 20.95 16,351 79.05
 Income (percentiles)
  0–29% 873 0.05 1,784,071 99.95 <0.0001b 873 20.45 3395 79.55 0.2938b
  30–59% 1310 0.05 2,612,723 99.95   1310 21.49 4785 78.51
  60%+ 4436 0.07 6,621,135 99.93   4436 21.52 16,180 78.48
 Year
  2003 317 0.03 1,016,565 99.97 <0.0001b 317 40.80 460 59.20 <0.0001b
  2004 287 0.03 1,015,716 99.97   287 26.70 788 73.30
  2005 319 0.03 1,015,929 99.97   319 23.74 1025 76.26
  2006 374 0.04 1,001,078 99.96   374 23.29 1232 76.71
  2007 497 0.05 1,019,688 99.95   497 22.42 1720 77.58
  2008 588 0.06 999,651 99.94   588 22.13 2069 77.87
  2009 771 0.08 997,219 99.92   771 24.12 2425 75.88
  2010 751 0.08 1,000,753 99.93   751 19.37 3126 80.63
  2011 884 0.09 983,859 99.91   884 20.49 3430 79.51
  2012 941 0.10 983,065 99.90   941 19.37 3918 80.63
  2013 890 0.09 984,406 99.91   890 17.60 4167 82.40
 Region (distance from Seoul)
  Gangwon-do (100.6 km) 115 0.04 321,209 99.96 <0.0001b 115 20.25 453 79.75 <0.0001b
  Gyeonggi-do (40.0 km) 1445 0.06 2,528,926 99.94   1445 21.80 5182 78.20
  Gyeongsangnam-do (366.4 km) 335 0.05 653,458 99.95   335 20.68 1285 79.32
  Gyeongsangbuk-do (225.5 km) 303 0.05 595,692 99.95   303 22.35 1053 77.65
  Gwangju (295.3 km) 272 0.08 324,124 99.92   272 14.48 1607 85.52
  Daegu (288.3 km) 432 0.08 561,837 99.92   432 17.63 2019 82.37
  Daejeon (160.9 km) 267 0.08 334,572 99.92   267 28.13 682 71.87
  Busan (394.2 km) 440 0.05 807,140 99.95   440 19.32 1837 80.68
  Seoul 1504 0.07 2,282,278 99.93   1504 24.78 4566 75.22
  Ulsan (395.7 km) 184 0.07 259,663 99.93   184 24.02 582 75.98
  Incheon (37.7 km) 265 0.04 606,840 99.96   265 23.47 864 76.53
  Jeollanam-do (346.3 km) 382 0.09 429,219 99.91   382 17.54 1796 82.46
  Jeollabuk-do (216.9 km) 244 0.06 413,454 99.94   244 18.26 1092 81.74
  Jeju-do (541.6 km) 69 0.06 123,336 99.94   69 23.31 227 76.69
  Chungcheongnam-do (129.9 km) 226 0.05 437,945 99.95   226 24.73 688 75.27
  Chungcheongbuk-do (137.1 km) 136 0.04 338,236 99.96   136 24.16 427 75.84
 Total 6619 0.06 11,017,929 99.98   6619 21.37 24,360 78.63  
  1. aThe results of analysis of variance (ANOVA) for each continuous variable to compare mean and standard deviation by diagnosis during study period
  2. bThe results of χ2 tests to analyze frequencies of person-years for each categorical variable by diagnosis of thyroid cancer