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The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells

  • Sergey A. Dyshlovoy1, 2, 3Email author,
  • Ramin Madanchi1,
  • Jessica Hauschild1,
  • Katharina Otte1,
  • Winfried H. Alsdorf1,
  • Udo Schumacher4,
  • Vladimir I. Kalinin2,
  • Alexandra S. Silchenko2,
  • Sergey A. Avilov2,
  • Friedemann Honecker1, 5,
  • Valentin A. Stonik2,
  • Carsten Bokemeyer1 and
  • Gunhild von Amsberg1
Contributed equally
BMC Cancer201717:93

https://doi.org/10.1186/s12885-017-3085-z

Received: 31 August 2016

Accepted: 23 January 2017

Published: 1 February 2017

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
31 Aug 2016 Submitted Original manuscript
15 Oct 2016 Reviewed Reviewer Report - Niklas Finnberg
17 Oct 2016 Reviewed Reviewer Report - Linara Gabitova
24 Oct 2016 Author responded Author comments - Sergey Dyshlovoy
Resubmission - Version 2
24 Oct 2016 Submitted Manuscript version 2
12 Jan 2017 Author responded Author comments - Sergey Dyshlovoy
Resubmission - Version 3
12 Jan 2017 Submitted Manuscript version 3
Publishing
23 Jan 2017 Editorially accepted
1 Feb 2017 Article published 10.1186/s12885-017-3085-z

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Medical Center Hamburg-Eppendorf
(2)
Laboratory of Marine Natural Products Chemistry, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-East Branch, Russian Academy of Sciences
(3)
School of Natural Sciences, Far Eastern Federal University
(4)
Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf
(5)
Tumor and Breast Center ZeTuP St. Gallen

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