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Table 2 Adverse events by grade in this phase-I study

From: BK-UM in patients with recurrent ovarian cancer or peritoneal cancer: a first-in-human phase-I study

  Level 1 Level 2 Level 3
Patient no. 1 2 3 4 5 6 7 8 9 10 11
Appetite loss 2 2          
General fatigue          2   
Nausea   2        2   
Vomiting   2        2   
Ileus   2     3      
Constipation 2      2    2   
Diarrhea       2      
Abdominal pain   2     2      
Abdominal fullness 2      3      
Intraabdominal bleeding           2  
Lumbago       2      
Headache       2      
Fever       2c 2c     
Dyspnea          2   
Hematomaa        2     
Erythema          2   
Anemia 2    2 2 3 2     
Elevation of ALT        2     
Elevation of CRP    2     2c 2c    
Hypoalbuminemia 2   2         
Hypotensionb         3c    3c
  1. aHematoma in the inserted port
  2. bTransient hypotension accompanied by abdominal peritoneal irritation
  3. cAdverse events during the administration of BK-UM
  4. No asterisk in adverse events indicates events monitored during the observation period after the administration of BK-UM